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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPB41L5
All Species:
36.97
Human Site:
S125
Identified Species:
62.56
UniProt:
Q9HCM4
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCM4
NP_065960.2
733
81856
S125
L
R
V
K
F
Y
S
S
E
P
N
N
L
R
E
Chimpanzee
Pan troglodytes
XP_001157953
733
81845
S125
L
R
V
K
F
Y
S
S
E
P
N
N
L
R
E
Rhesus Macaque
Macaca mulatta
XP_001088764
726
81122
S125
L
R
V
K
F
Y
S
S
E
P
N
N
L
R
E
Dog
Lupus familis
XP_532028
914
101864
S207
F
R
V
K
Y
Y
S
S
E
P
N
N
L
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGS1
731
81617
S125
L
R
V
K
F
Y
S
S
E
P
N
N
L
R
E
Rat
Rattus norvegicus
Q5FVG2
731
81700
S125
L
R
V
K
F
Y
S
S
E
P
N
N
L
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509941
820
90648
E138
A
I
F
E
K
W
K
E
Y
R
S
Q
T
P
A
Chicken
Gallus gallus
XP_422083
502
57358
Frog
Xenopus laevis
NP_001080234
498
57093
Zebra Danio
Brachydanio rerio
O57457
619
70690
T36
Q
Q
G
I
K
K
S
T
R
G
S
V
V
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650291
972
105216
S140
L
K
V
K
F
Y
S
S
E
P
N
T
L
R
E
Honey Bee
Apis mellifera
XP_623974
809
90976
S204
L
K
V
K
F
Y
S
S
E
P
N
T
L
R
E
Nematode Worm
Caenorhab. elegans
P28191
1026
115075
W259
I
K
M
N
E
Y
A
W
V
R
I
R
K
L
S
Sea Urchin
Strong. purpuratus
XP_788387
843
92835
S120
F
Q
V
K
F
Y
S
S
E
P
N
N
L
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
95.2
39.8
N.A.
83.9
83.6
N.A.
56.5
56.6
54.4
28.5
N.A.
36.8
38.9
24.3
39.1
Protein Similarity:
100
99.3
96.3
52.1
N.A.
89.2
88.4
N.A.
65.1
62.2
60.9
44.7
N.A.
51.8
53.1
40.1
56.7
P-Site Identity:
100
100
100
86.6
N.A.
100
100
N.A.
0
0
0
6.6
N.A.
86.6
86.6
6.6
86.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
20
0
0
40
N.A.
93.3
93.3
33.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
0
8
8
0
0
8
65
0
0
0
0
0
65
% E
% Phe:
15
0
8
0
58
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
0
8
0
0
0
0
0
0
8
0
0
0
0
% I
% Lys:
0
22
0
65
15
8
8
0
0
0
0
0
8
0
0
% K
% Leu:
50
0
0
0
0
0
0
0
0
0
0
0
65
15
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
65
50
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
65
0
0
0
8
0
% P
% Gln:
8
15
0
0
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
43
0
0
0
0
0
0
8
15
0
8
0
65
0
% R
% Ser:
0
0
0
0
0
0
72
65
0
0
15
0
0
0
8
% S
% Thr:
0
0
0
0
0
0
0
8
0
0
0
15
8
0
0
% T
% Val:
0
0
65
0
0
0
0
0
8
0
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
72
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _